NIMBioS: Mathematical Simulation of Open-heart Surgery Lends Clues to Kidney Failure

NIMBioS_kidneyNearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it.

Now, for the first time, a team of international researchers—including those from the National Institute for Mathematical and Biological Synthesis (NIMBioS) based at UT—have investigated the causes of kidney injury, using a mathematical model that simulates typical open-heart surgery and the effects on a rat kidney. The model uses algorithms to simulate the transport of fluids through the kidney’s inner and outer regions and the ureter, the tube that carries urine to the bladder.

The study was published this week in the journal Mathematical Medicine and Biology.

Continue reading on the NIMBioS website.